A Clinical, Pathological and Biochemical Study of Amyloid Nephrosis.

The conception of a degenerative form of nephritis as opposed to the common inflammatory form, whether justified or not, has been the source of many valuable observations on the clinical, chemical and histological aspects of the subject. The term nephrosis " was introduced by Aiiller(l) to indicate the purely degenerative form, and since the degeneration is frequently of the fatty type, the term " lipoid nephrosis " has been use(l by many writers on the subject. It appears, however, that there is no hard and fast line between ordinary glomerulonephritis and nephrosis, and that all combinations of glomerular and vascular inflammation with tubular degeneration may be found. Nevertheless it remains convenient to distinguish a group in w-hich the signs of inflammation are conspicuously small.